Your challenge

This project aims to unravel the role of aging-regulated non-coding RNAs in controlling cardiovascular aging. Aging is the main cause of cardiovascular disease and the main type of heart failure that is caused by aging is heart failure with preserved ejection fraction. Currently there is no treatment for this disease and the underlying causes are also not clear. Recently, it has been shown that the non-coding part of the genome is transcribed in RNA and that these so-called non-coding RNAs contribute to cellular processes, including aging. In this project we aim to unravel the role of these non-coding RNAs in heart failure with preserved ejection fraction.

As a PhD student your main responsibilities are to:

  • Work in close collaboration with the members of your international research groups at Amsterdam UMC;
  • Perform molecular and cellular biology, as well as in vivo experiments;
  • Successfully complete your PhD training program and publish in renowned journals.

Your profile

We are looking for a PhD student with the following experience:

  • You have an Msc degree in molecular cell biology, biochemistry or medical biology;
  • Research experience abroad is a plus;
  • Experience with bioinformatics and next generation sequencing data is a plus;
  • Experience with cardiovascular in vivo models is a plus;
  • Experience in molecular cell biology is a plus.

You are a highly motivated and enthusiastic MSc graduate with a strong interest (and experience) in bioinformatics. You are proactive and precise, result-oriented, and care about the quality of your work, have excellent (written) English communication skills, and work optimally when collaborating with others. Last but not least you like to solve scientific problems in an innovative way and have intrinsic motivation and the capacity to continuously improve yourself.

Your work environment

The Department of Physiology at the Amsterdam University Medical Centers focuses on research on cardiovascular disease. The research at the physiology department is characterized by a multi-disciplinary approach with strong interaction between fundamental and clinical studies. You will work in close collaboration with fellow PhD students, Postdocs, Reaseach Technicians and staff members of the team.

Working at Amsterdam UMC means working in an inspiring and professional environment where developing one`s talents and academic skills are encouraged. We offer you ample opportunity for development, deepening and broadening, additional training, and a place to grow!

We offer

Salary Scale PHD: 2495 tot 3196 euro gross when employed full-time (depending on qualifications and experience).

Salary scale: PhD (2495 to 3196 euro based on a 36 hour week), depending on qualifications and experience.
In addition, we offer:
– Additional benefits include an 8.3% end-of-year bonus and 8.0% holiday pay.
– The opportunity to follow further training and development.
– Pension is accrued at the ABP. VUmc contributes a large part of the premium (70%).
– In addition to excellent accessibility by public transport, we reimburse 75% of your public transport costs (commuting costs).

We offer an initial contract for 12 months that will be extended (after evaluation) for another 36 months.

For more information about our employment conditions, please visit our website.

Dutch residents who will start working at VU University Medical Center will have to hand in a VOG before starting work. You need to have a DigID to be able to apply for a VOG.

Additional information

The prospective start date is: 01-10-2021

Be sure to provide in your motivation letter and/or CV a brief summary of major accomplishments, a brief description of your research experience and 2 references with their contact details.

Information and application

Don’t hesitate to call us!
If you’re interested about this position, you can contact Prof. dr. Reinier Boon, via telephone number 06-54 202 007.
If you need more information about the application procedure, contact Brend de Jong, corporate recruiter at 020 444 8704.

You can apply till 4 July 2021 by using the apply button.

Acquisition based on this vacancy is not appreciated.