In the context of a project recently funded by the Public-Private Partnership program (TKI-PPP), your research will be dedicated to the development of a molecular test for anal cancer screening in patients with an increased anal cancer risk, such as HIV+ men having sex with men. Our recent studies on anal tissues demonstrate the diagnostic value of epigenetic biomarkers based on DNA methylation for the detection of anal cancer and its precursors. This project aims to translate these findings to anal screening strategies. You will perform a genome wide discovery screen, using 850K Infinium MethylationEPIC Arrays on anal swabs. Following candidate selection and verification studies, you will develop a PCR-based assay applicable to anal swabs. The wide range of projects in our research group offers opportunities for various parallel research questions to be addressed.
The TKI-PPP project will be carried out in close collaboration with scientists, clinicians and biostatisticians at the Depts. of Pathology, Dermatology, Infectious Diseases and Epidemiology and Data Science and the company Self-screen BV.
We are looking for an ambitious postdoc with a strong background and publication record in translational cancer research and molecular biology. We expect you to be highly self-motivated, creative, and be able to work in a team. You should exhibit a high degree of independence, a problem-solving attitude and have strong analytical and technical abilities.
In addition you meet the following requirements:
- PhD in molecular cancer research and/or biomarker research;
- Knowledge on cancer biomarkers, epigenetics and experience with genome wide data analysis and methylation assays are an advantage;
- Excellent communication and writing skills;
- Fluency in spoken English and proficiency in writing are recommended.
Your work environment
At the Cancer Cancer Amsterdam in Amsterdam UMC, the Molecular Pathology research group is one of the world’s leading translational research groups in the area of human papillomavirus (HPV)-induced carcinogenesis. Our research aims to unravel the molecular pathogenesis of HPV-induced cancer using cutting edge technologies. The gained molecular knowledge is translated into clinically applicable biomarker tests for (early) cancer detection and improving outcomes.
Working at Amsterdam UMC means working in an inspiring and professional environment in which developing one`s talents and skills is encouraged. We offer you ample opportunity for development, deepening and broadening, additional training and a place to grow!
Salary Scale 10: 2911 tot 4615 euro gross when employed full-time (depending on qualifications and experience).
In addition, we offer:
– Additional benefits include an 8.3% end-of-year bonus and 8.0% holiday pay.
– The opportunity to follow further training and development.
– Pension is accrued at the ABP. VUmc contributes a large part of the premium (70%).
– In addition to excellent accessibility by public transport, we reimburse 75% of your OV travel costs (commuting costs).
For more information about our employment conditions, please visit our website.
For Dutch citizens it is mandatory to provide a VOG (Verklaring Omtrent Gedrag). Foreign citizens need to provide comparable police clearing certificates.
The preferred starting date for this position is September or October 2021, but negotiable.
Information and application
Don’t hesitate to call us!
If you’re interested about this position, you can contact Renske Steenbergen, via telephone number 020-4442331.
If you need more information about the application procedure, contact Brend de Jong, corporate recruiter at 020-4445635.
You can apply till 8 August 2021 by using the apply button.
Acquisition based on this vacancy is not appreciated.